The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation Through the PI3K/AKT/CyclinD1 Signaling Pathway

Cholesteatoma is a chronic inflammatory ear disease with abnormal keratinized epithelium proliferation and tissue damage. However, the mechanism of keratinized epithelium hyperproliferation in cholesteatoma remains unknown. Hence, our study sought to shed light on mechanisms affecting the pathology...

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Detalles Bibliográficos
Autores principales: Gao, Miao, Xiao, Heng, Liang, Yonglan, Cai, Huimin, Guo, Xiaojing, Lin, Jianwei, Zhuang, Suling, Xu, Jianhua, Ye, Shengnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495652/
https://www.ncbi.nlm.nih.gov/pubmed/37532176
http://dx.doi.org/10.1016/j.mcpro.2023.100628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495652/
https://www.ncbi.nlm.nih.gov/pubmed/37532176
http://dx.doi.org/10.1016/j.mcpro.2023.100628

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