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Unbalanced redox status network as an early pathological event in congenital cataracts

The lens proteome undergoes dramatic composition changes during development and maturation. A defective developmental process leads to congenital cataracts that account for about 30% of cases of childhood blindness. Gene mutations are associated with approximately 50% of early-onset forms of lens op...

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Detalles Bibliográficos
Autores principales: Bejarano, Eloy, Whitcomb, Elizabeth A., Pfeiffer, Rebecca L., Rose, Kristie L., Asensio, Maria José, Rodríguez-Navarro, José Antonio, Ponce-Mora, Alejandro, Canto, Antolín, Almansa, Inma, Schey, Kevin L., Jones, Bryan W., Taylor, Allen, Rowan, Sheldon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495660/
https://www.ncbi.nlm.nih.gov/pubmed/37677999
http://dx.doi.org/10.1016/j.redox.2023.102869