Inhibition of the serine/threonine kinase BUB1 reverses taxane resistance in prostate cancer

Men with incurable castration resistant prostate cancer (CRPC) are typically treated with taxanes; however, drug resistance rapidly develops. We previously identified a clinically relevant seven gene network in aggressive CRPC, which includes the spindle assembly checkpoint (SAC) kinase BUB1. Since...

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Detalles Bibliográficos
Autores principales: Martinez, Maria J., Lyles, Rolando D.Z., Peinetti, Nahuel, Grunfeld, Alex M., Burnstein, Kerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495664/
https://www.ncbi.nlm.nih.gov/pubmed/37705955
http://dx.doi.org/10.1016/j.isci.2023.107681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495664/
https://www.ncbi.nlm.nih.gov/pubmed/37705955
http://dx.doi.org/10.1016/j.isci.2023.107681

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