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Reduced tubuloglomerular feedback activity and absence of its synchronization in a connexin40 knockout rat

Introduction: Tubuloglomerular feedback (TGF) is the negative feedback component of renal blood flow (RBF) autoregulation. Neighbouring nephrons often exhibit spontaneous TGF oscillation and synchronization mediated by endothelial communication, largely via connexin40 (Cx40). Methods: We had a knock...

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Detalles Bibliográficos
Autores principales: More, Heather L., Braam, Branko, Cupples, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495682/
https://www.ncbi.nlm.nih.gov/pubmed/37705697
http://dx.doi.org/10.3389/fnetp.2023.1208303