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Purification and Characterization of Mitochondrial Mg(2+)-Independent Sphingomyelinase from Rat Brain

Sphingomyelinase (SMase) catalyzes ceramide production from sphingomyelin. Ceramides are critical in cellular responses such as apoptosis. They enhance mitochondrial outer membrane permeabilization (MOMP) through self-assembly in the mitochondrial outer membrane to form channels that release cytochr...

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Detalles Bibliográficos
Autores principales: Choi, Jong Min, Piao, Yongwei, Ahn, Kyong Hoon, Kim, Seok Kyun, Won, Jong Hoon, Lee, Jae Hong, Jang, Ji Min, Shin, In Chul, Fu, Zhicheng, Jung, Sung Yun, Jeong, Eui Man, Kim, Dae Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495687/
https://www.ncbi.nlm.nih.gov/pubmed/37305954
http://dx.doi.org/10.14348/molcells.2023.0074