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Purification and Characterization of Mitochondrial Mg(2+)-Independent Sphingomyelinase from Rat Brain
Sphingomyelinase (SMase) catalyzes ceramide production from sphingomyelin. Ceramides are critical in cellular responses such as apoptosis. They enhance mitochondrial outer membrane permeabilization (MOMP) through self-assembly in the mitochondrial outer membrane to form channels that release cytochr...
Autores principales: | Choi, Jong Min, Piao, Yongwei, Ahn, Kyong Hoon, Kim, Seok Kyun, Won, Jong Hoon, Lee, Jae Hong, Jang, Ji Min, Shin, In Chul, Fu, Zhicheng, Jung, Sung Yun, Jeong, Eui Man, Kim, Dae Kyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495687/ https://www.ncbi.nlm.nih.gov/pubmed/37305954 http://dx.doi.org/10.14348/molcells.2023.0074 |
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