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Dasatinib suppresses particulate-induced pyroptosis and acute lung inflammation

Background: Humans are constantly exposed to various industrial, environmental, and endogenous particulates that result in inflammatory diseases. After being engulfed by immune cells, viz. Macrophages, such particulates lead to phagolysosomal dysfunction, eventually inducing pyroptosis, a form of ce...

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Detalles Bibliográficos
Autores principales: Pan, Yixi, Ikoma, Kenta, Matsui, Risa, Nakayama, Akiyoshi, Takemura, Naoki, Saitoh, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495768/
https://www.ncbi.nlm.nih.gov/pubmed/37705538
http://dx.doi.org/10.3389/fphar.2023.1250383