Novel T cell/organoid culture system allows ex vivo modeling of intestinal graft-versus-host disease

Acute graft-versus-host disease (GvHD) remains the biggest clinical challenge and prognosis-determining complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Donor T cells are acceptedly key mediators of alloreactivity against host tissues and here especially the gut. In...

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Detalles Bibliográficos
Autores principales: Matthe, Diana M., Dinkel, Martin, Schmid, Benjamin, Vogler, Tina, Neurath, Markus F., Poeck, Hendrik, Neufert, Clemens, Büttner-Herold, Maike, Hildner, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495981/
https://www.ncbi.nlm.nih.gov/pubmed/37705975
http://dx.doi.org/10.3389/fimmu.2023.1253514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495981/
https://www.ncbi.nlm.nih.gov/pubmed/37705975
http://dx.doi.org/10.3389/fimmu.2023.1253514

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