Cargando…

Novel T cell/organoid culture system allows ex vivo modeling of intestinal graft-versus-host disease

Acute graft-versus-host disease (GvHD) remains the biggest clinical challenge and prognosis-determining complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Donor T cells are acceptedly key mediators of alloreactivity against host tissues and here especially the gut. In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matthe, Diana M., Dinkel, Martin, Schmid, Benjamin, Vogler, Tina, Neurath, Markus F., Poeck, Hendrik, Neufert, Clemens, Büttner-Herold, Maike, Hildner, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495981/ https://www.ncbi.nlm.nih.gov/pubmed/37705975 http://dx.doi.org/10.3389/fimmu.2023.1253514

Ejemplares similares

Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration
por: Enderle, Karin, et al.
Publicado: (2021)

Th17 Cell-Mediated Colitis Is Positively Regulated by Interferon Regulatory Factor 4 in a T Cell-Extrinsic Manner
por: Buchele, Vera, et al.
Publicado: (2021)

Targeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis
por: Buchele, Vera, et al.
Publicado: (2018)

Intestinal ex vivo organoid culture reveals altered programmed crypt stem cells in patients with celiac disease
por: Dieterich, Walburga, et al.
Publicado: (2020)

Round-Robin test for the histological diagnosis of acute colonic Graft-versus-Host disease validating established histological criteria and grading systems
por: Hippe, Katrin, et al.
Publicado: (2023)

The Role of Pattern-Recognition Receptors in Graft-Versus-Host Disease and Graft-Versus-Leukemia after Allogeneic Stem Cell Transplantation
por: Heidegger, Simon, et al.
Publicado: (2014)

Complexity of Secretory Chemokines in Human Intestinal Organoid Cultures Ex Vivo
por: COTTLE, C., et al.
Publicado: (2022)

Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytes
por: Nozaki, Kengo, et al.
Publicado: (2016)

From Clones to Buds and Branches: The Use of Lung Organoids to Model Branching Morphogenesis Ex Vivo
por: Vazquez-Armendariz, Ana Ivonne, et al.
Publicado: (2021)

Endomicroscopic Imaging of COX-2 Activity in Murine Sporadic and Colitis-Associated Colorectal Cancer
por: Foersch, Sebastian, et al.
Publicado: (2013)

Isolated thrombotic microangiopathy of the small intestine in a patient with atypical hemolytic uremic syndrome – a case report
por: Nunius, Christoph, et al.
Publicado: (2020)

Immuno-fluorescent Labeling of Microtubules and Centrosomal Proteins in Ex Vivo Intestinal Tissue and 3D In Vitro Intestinal Organoids
por: Goldspink, Deborah A., et al.
Publicado: (2017)

Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice
por: Heichler, Christina, et al.
Publicado: (2022)

Murine cytomegalovirus reactivation concomitant with acute graft-versus-host disease is controlled by antibodies
por: Seefried, Martina, et al.
Publicado: (2023)

Intestinal Organoids in Colitis Research: Focusing on Variability and Cryopreservation
por: zur Bruegge, Talke F., et al.
Publicado: (2021)

Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders
por: Wiesinger, Manuel, et al.
Publicado: (2017)

An investigation of the diagnostic, predictive, and prognostic impacts of three colonic biopsy grading systems for acute graft versus host disease
por: Kreft, Andreas, et al.
Publicado: (2021)

Expansion of IL-23 receptor bearing TNFR2+ T cells is associated with molecular resistance to anti-TNF therapy in Crohn’s disease
por: Schmitt, Heike, et al.
Publicado: (2019)

Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine
por: Heidbreder, Karin, et al.
Publicado: (2023)

Nanoblades allow high-level genome editing in murine and human organoids
por: Tiroille, Victor, et al.
Publicado: (2023)

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
por: Pickert, Geethanjali, et al.
Publicado: (2009)

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
por: Grabinger, T, et al.
Publicado: (2014)

Intestinal organoids in farm animals
por: Beaumont, Martin, et al.
Publicado: (2021)

Standard: Human intestinal organoids
por: Wang, Yalong, et al.
Publicado: (2023)

Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis
por: Koop, Kristina, et al.
Publicado: (2023)

Methylene Blue-Aided In Vivo Staining of Central Airways during Flexible Bronchoscopy
por: Zirlik, Sabine, et al.
Publicado: (2012)

Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers
por: Kardia, Egi, et al.
Publicado: (2021)

Cerebral organoids: emerging ex vivo humanoid models of glioblastoma
por: Papaioannou, Michail-Dimitrios, et al.
Publicado: (2020)

Comparison of Hemospray(®) and Endoclot(™) for the treatment of gastrointestinal bleeding
por: Vitali, Francesco, et al.
Publicado: (2019)

Retrograde inspection vs standard forward view for the detection of colorectal adenomas during colonoscopy: A back-to-back randomized clinical trial
por: Rath, Timo, et al.
Publicado: (2020)

Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis
por: Lindemann, Aylin, et al.
Publicado: (2023)

Grundlagen der Nierenpathologie für Pathologen – Teil 2: Nichtentzündliche Veränderungen
por: Gaspert, Ariana, et al.
Publicado: (2023)

Intestinal IgA-positive plasma cells are highly sensitive indicators of alloreaction early after allogeneic transplantation and associate with both graft-versus-host disease and relapse-related mortality
por: Scheidler, Lucia, et al.
Publicado: (2023)

ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure
por: Schulz-Kuhnt, Anja, et al.
Publicado: (2020)

DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets
por: Wilson, Sean B., et al.
Publicado: (2022)

Organoids in gastrointestinal diseases: from experimental models to clinical translation
por: Günther, Claudia, et al.
Publicado: (2022)

Intestinal Organoids—Current and Future Applications
por: Meneses, Andre M. C., et al.
Publicado: (2016)

Phenotypic landscape of intestinal organoid regeneration
por: Lukonin, Ilya, et al.
Publicado: (2020)

Human Intestinal Organoids: Promise and Challenge
por: Taelman, Jasin, et al.
Publicado: (2022)

Standard: Human intestinal cancer organoids
por: Lin, Hanqing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sq41vi4s43iuaj7gpgfmahog6q