Alterations in the gut microbiome and its metabolites are associated with the immune response to mucosal immunization with Lactiplantibacillus plantarum-displaying recombinant SARS-CoV-2 spike epitopes in mice

Lactic acid bacteria (LAB) expressing foreign antigens have great potential as mucosal vaccines. Our previous study reported that recombinant Lactiplantibacillus plantarum SK156 displaying SARS-CoV-2 spike S1 epitopes elicited humoral and cell-mediated immune responses in mice. Here, we further exam...

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Detalles Bibliográficos
Autores principales: Hwang, In-Chan, Vasquez, Robie, Song, Ji Hoon, Engstrand, Lars, Valeriano, Valerie Diane, Kang, Dae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495993/
https://www.ncbi.nlm.nih.gov/pubmed/37705931
http://dx.doi.org/10.3389/fcimb.2023.1242681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495993/
https://www.ncbi.nlm.nih.gov/pubmed/37705931
http://dx.doi.org/10.3389/fcimb.2023.1242681

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