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Asymmetric Synthesis of Functionalizable Type II β-Turn-Inducing α-Amino Acid Building Blocks

[Image: see text] Peptidomimetics are emerging as a promising class of potent and selective therapeutics. Among the current approaches to these compounds, the utilization of constrained lactams is a key element in enforcing the active peptide conformation, and the development of efficient and stereo...

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Detalles Bibliográficos
Autores principales: Gao, Wenzheng, Han, Jiaxin, Greaves, Sophie, Harrity, Joseph P. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496131/
https://www.ncbi.nlm.nih.gov/pubmed/37642309
http://dx.doi.org/10.1021/acs.orglett.3c02376