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Promiscuous Enzymes for Residue-Specific Peptide and Protein Late-Stage Functionalization

The late-stage functionalization of peptides and proteins holds significant promise for drug discovery and facilitates bioorthogonal chemistry. This selective functionalization leads to innovative advances in in vitro and in vivo biological research. However, it is a challenging endeavor to selectiv...

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Detalles Bibliográficos
Autores principales: Alexander, Ashley K., Elshahawi, Sherif I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496146/
https://www.ncbi.nlm.nih.gov/pubmed/37338668
http://dx.doi.org/10.1002/cbic.202300372