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A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection

BACKGROUND: Varicella zoster virus (VZV), which is a human restricted alpha-herpesvirus, causes varicella (chickenpox) and zoster (shingles). The subsequent post-herpetic neuralgia (PHN) due to VZV infection is excruciating for most patients. Thus, developing specific therapeutics against VZV infect...

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Detalles Bibliográficos
Autores principales: Pei, Jiawei, Tian, Ye, Ye, Wei, Han, Jiangfan, Dang, Yamei, Cheng, Tong, Wang, Wei, Zhao, Yipu, Ye, Weiliang, Huangfu, Shuyuan, Li, Yu, Zhang, Fanglin, Lei, Yingfeng, Qian, Airong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496174/
https://www.ncbi.nlm.nih.gov/pubmed/37700336
http://dx.doi.org/10.1186/s13578-023-01108-1