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ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data
Clustering is a critical component of single-cell RNA sequencing (scRNA-seq) data analysis and can help reveal cell types and infer cell lineages. Despite considerable successes, there are few methods tailored to investigating cluster-specific genes contributing to cell heterogeneity, which can prom...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496184/ https://www.ncbi.nlm.nih.gov/pubmed/37697330 http://dx.doi.org/10.1186/s13059-023-03046-0 |