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ZINBMM: a general mixture model for simultaneous clustering and gene selection using single-cell transcriptomic data

Clustering is a critical component of single-cell RNA sequencing (scRNA-seq) data analysis and can help reveal cell types and infer cell lineages. Despite considerable successes, there are few methods tailored to investigating cluster-specific genes contributing to cell heterogeneity, which can prom...

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Detalles Bibliográficos
Autores principales: Li, Yang, Wu, Mingcong, Ma, Shuangge, Wu, Mengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496184/
https://www.ncbi.nlm.nih.gov/pubmed/37697330
http://dx.doi.org/10.1186/s13059-023-03046-0