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Tranexamic acid for haemostasis and beyond: does dose matter?

Tranexamic acid (TXA) is a widely used antifibrinolytic agent that has been used since the 1960’s to reduce blood loss in various conditions. TXA is a lysine analogue that competes for the lysine binding sites in plasminogen and tissue-type plasminogen activator impairing its interaction with the ex...

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Detalles Bibliográficos
Autores principales: Lam, Tammy, Medcalf, Robert L., Cloud, Geoffrey C., Myles, Paul S., Keragala, Charithani B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496216/
https://www.ncbi.nlm.nih.gov/pubmed/37700271
http://dx.doi.org/10.1186/s12959-023-00540-0