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Effect of high-dose intravenous ascorbic acid on microcirculation and endothelial glycocalyx during sepsis and septic shock: a double-blind, randomized, placebo-controlled study

Previous studies indicate supplemental vitamin C improves microcirculation and reduces glycocalyx shedding in septic animals. Our randomized, double-blind, placebo-controlled trial aimed to investigate whether a high dose of intravenous ascorbic acid (AA) might improve microcirculation and affect gl...

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Detalles Bibliográficos
Autores principales: Belousoviene, Egle, Pranskuniene, Zivile, Vaitkaitiene, Egle, Pilvinis, Vidas, Pranskunas, Andrius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496271/
https://www.ncbi.nlm.nih.gov/pubmed/37700249
http://dx.doi.org/10.1186/s12871-023-02265-z