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Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages

TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of brain tumors. However, due to the heterogeneity of cell populations that contribute to the TSPO-PET signal, imaging interpretation may be challenging. We therefore evaluated TSPO enrichment/expression in connec...

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Detalles Bibliográficos
Autores principales: Weidner, Lorraine, Lorenz, Julia, Quach, Stefanie, Braun, Frank K., Rothhammer-Hampl, Tanja, Ammer, Laura-Marie, Vollmann-Zwerenz, Arabel, Bartos, Laura M., Dekorsy, Franziska J., Holzgreve, Adrien, Kirchleitner, Sabrina V., Thon, Niklas, Greve, Tobias, Ruf, Viktoria, Herms, Jochen, Bader, Stefanie, Milenkovic, Vladimir M., von Baumgarten, Louisa, Menevse, Ayse N., Hussein, Abir, Sax, Julian, Wetzel, Christian H., Rupprecht, Rainer, Proescholdt, Martin, Schmidt, Nils O., Beckhove, Philipp, Hau, Peter, Tonn, Joerg-Christian, Bartenstein, Peter, Brendel, Matthias, Albert, Nathalie L., Riemenschneider, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496331/
https://www.ncbi.nlm.nih.gov/pubmed/37697350
http://dx.doi.org/10.1186/s40478-023-01651-5