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Gut microbiota of old mice worsens neurological outcome after brain ischemia via increased valeric acid and IL-17 in the blood

BACKGROUND: Aging is a significant risk factor for ischemic stroke and worsens its outcome. However, the mechanisms for this worsened neurological outcome with aging are not clearly defined. RESULTS: Old C57BL/6J male mice (18 to 20 months old) had a poorer neurological outcome and more severe infla...

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Detalles Bibliográficos
Autores principales: Zeng, Xianzhang, Li, Jun, Shan, Weiran, Lai, Zhongmeng, Zuo, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496352/
https://www.ncbi.nlm.nih.gov/pubmed/37697393
http://dx.doi.org/10.1186/s40168-023-01648-1