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Gut microbiota of old mice worsens neurological outcome after brain ischemia via increased valeric acid and IL-17 in the blood
BACKGROUND: Aging is a significant risk factor for ischemic stroke and worsens its outcome. However, the mechanisms for this worsened neurological outcome with aging are not clearly defined. RESULTS: Old C57BL/6J male mice (18 to 20 months old) had a poorer neurological outcome and more severe infla...
Autores principales: | Zeng, Xianzhang, Li, Jun, Shan, Weiran, Lai, Zhongmeng, Zuo, Zhiyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496352/ https://www.ncbi.nlm.nih.gov/pubmed/37697393 http://dx.doi.org/10.1186/s40168-023-01648-1 |
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