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A novel 3D bilayer hydrogel tri-culture system for studying functional motor units

BACKGROUND: A motor unit (MU) is formed by a single alpha motor neuron (MN) and the muscle fibers it innervates. The MU is essential for all voluntary movements. Functional deficits in the MU result in neuromuscular disorders (NMDs). The pathological mechanisms underlying most NMDs remain poorly und...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Lung, Nhieu, Jennifer, Lerdall, Thomas, Milbauer, Liming, Wei, Chin-Wen, Lee, Dong Jun, Oh, Sang-Hyun, Thayer, Stanley, Wei, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496371/
https://www.ncbi.nlm.nih.gov/pubmed/37700376
http://dx.doi.org/10.1186/s13578-023-01115-2