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Inhibition of COX-2 signaling favors E. coli during urinary tract infection

BACKGROUND: To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and as an alternative treatment for uncomplicated urinary tract infections (UTIs). However, clinical studies evaluating NSAIDs ve...

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Detalles Bibliográficos
Autores principales: Mohanty, Soumitra, Lindelauf, Ciska, White, John Kerr, Scheffschick, Andrea, Ehrenborg, Ewa, Demirel, Isak, Brauner, Hanna, Brauner, Annelie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496388/
https://www.ncbi.nlm.nih.gov/pubmed/37697284
http://dx.doi.org/10.1186/s12950-023-00356-9