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LncRNA PTTG3P promotes tumorigenesis and metastasis of NSCLC by binding with ILF3 to maintain mRNA stability and form a positive feedback loop with E2F1

Non-small cell lung cancer (NSCLC) is a highly lethal disease worldwide. We found the pseudogene-derived lncRNA PTTG3P is upregulated in NSCLC and associated with larger tumor size, advanced staging, and poor prognosis. This study investigated the oncogenic roles and mechanisms of PTTG3P in NSCLC. W...

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Detalles Bibliográficos
Autores principales: Wang, Jing, He, Xuezhi, Yao, Qing, Wang, Chan, Lu, Xiyi, Wang, Rong, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496499/
https://www.ncbi.nlm.nih.gov/pubmed/37705754
http://dx.doi.org/10.7150/ijbs.81738