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IκB kinase β (IKKβ): Structure, transduction mechanism, biological function, and discovery of its inhibitors

The effective approach to discover innovative drugs will ask natural products for answers because of their complex and changeable structures and multiple biological activities. Inhibitory kappa B kinase beta (IKKβ), known as IKK2, is a key regulatory kinase responsible for the activation of NF-κB th...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zhang, Rui, Li, Wei, Ma, Xiao-Chi, Qiu, Feng, Sun, Cheng-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496512/
https://www.ncbi.nlm.nih.gov/pubmed/37705738
http://dx.doi.org/10.7150/ijbs.85158