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Association of functional, inherited vitamin D–binding protein variants with melanoma-specific death

BACKGROUND: It is unclear whether genetic variants affecting vitamin D metabolism are associated with melanoma prognosis. Two functional missense variants in the vitamin D–binding protein gene (GC), rs7041 and rs4588, determine 3 common haplotypes, Gc1s, Gc1f, and Gc2, of which Gc1f may be associate...

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Detalles Bibliográficos
Autores principales: Gibbs, David Corley, Thomas, Nancy E, Kanetsky, Peter A, Luo, Li, Busam, Klaus J, Cust, Anne E, Anton-Culver, Hoda, Gallagher, Richard P, Zanetti, Roberto, Rosso, Stefano, Sacchetto, Lidia, Edmiston, Sharon N, Conway, Kathleen, Ollila, David W, Begg, Colin B, Berwick, Marianne, Ward, Sarah V, Orlow, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496570/
https://www.ncbi.nlm.nih.gov/pubmed/37494457
http://dx.doi.org/10.1093/jncics/pkad051