Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication

Ebola virus (EBOV) critically depends on the viral polymerase to replicate and transcribe the viral RNA genome in the cytoplasm of host cells, where cellular factors can antagonize or facilitate the virus life cycle. Here we leverage proximity proteomics and conduct a small interfering RNA (siRNA) s...

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Detalles Bibliográficos
Autores principales: Fang, Jingru, Pietzsch, Colette, Tsaprailis, George, Crynen, Gogce, Cho, Kelvin Frank, Ting, Alice Y., Bukreyev, Alexander, de la Torre, Juan Carlos, Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496643/
https://www.ncbi.nlm.nih.gov/pubmed/35320713
http://dx.doi.org/10.1016/j.celrep.2022.110544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496643/
https://www.ncbi.nlm.nih.gov/pubmed/35320713
http://dx.doi.org/10.1016/j.celrep.2022.110544

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