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Effect of melatonin in patients with low anterior resection syndrome (MELLARS): a study protocol for a randomised, placebo-controlled, crossover trial

INTRODUCTION: After rectal cancer surgery, a majority of patients suffer from sequelae known as low anterior resection syndrome (LARS). It is a collection of symptoms consisting of flatus and/or stool incontinence, evacuation frequency, re-evacuation and urgency. The circadian hormone, melatonin, ha...

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Detalles Bibliográficos
Autores principales: Zahid, Jawad Ahmad, Madsen, Michael Tvilling, Bulut, Orhan, Christensen, Peter, Gögenur, Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496695/
https://www.ncbi.nlm.nih.gov/pubmed/37696629
http://dx.doi.org/10.1136/bmjopen-2022-067763