Pharmacokinetic Assessment of Pyrazinamide and Pyrazinoic Acid in Carbon tetrachloride-induced Liver Injury Model in Wistar Rats

BACKGROUND: We investigated the pharmacokinetic behavior of pyrazinamide (PZA) and pyrazinoic acid (PA) in the presence of carbon-tetrachloride (CCl(4)) plus antitubercular treatment (ATT) drug-induced liver injury (DILI) in rats. METHODS: Thirty rats utilized in the experiment were separated equall...

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Detalles Bibliográficos
Autores principales: Sharma, Swati, Sharma, Vishal, Taneja, Sunil, Bhatia, Alka, Anand, Aishwarya, Banerjee, Dibyajyoti, Patil, Amol N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496854/
https://www.ncbi.nlm.nih.gov/pubmed/37705855
http://dx.doi.org/10.4103/jpbs.jpbs_333_23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496854/
https://www.ncbi.nlm.nih.gov/pubmed/37705855
http://dx.doi.org/10.4103/jpbs.jpbs_333_23

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