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m(6)A methyltransferase METTL16 mediates immune evasion of colorectal cancer cells via epigenetically regulating PD-L1 expression

Background: The immune checkpoint inhibitors (ICIs) has dramatically changed the therapeutic area of cancers. A great number of patients with CRC exhibit poor response rate to ICI treatment. N6-methyl adenosine (m6A) is closely correlated with the initiation and progression of cancers. To explore th...

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Detalles Bibliográficos
Autores principales: Wang, Ailei, Sun, Yingjie, Wang, Xince, Yan, Zhaofei, Wang, Dongsheng, Zeng, Li, Lu, Qingge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496997/
https://www.ncbi.nlm.nih.gov/pubmed/37647025
http://dx.doi.org/10.18632/aging.204980