Primary hypertrophic osteoarthropathy: genetics, clinical features and management

Primary hypertrophic osteoarthropathy (PHO) is a genetic disorder mainly characterized by clubbing fingers, pachydermia and periostosis. Mutations in the HPGD or SLCO2A1 gene lead to impaired prostaglandin E2 (PGE2) degradation, thus elevating PGE2 levels. The identification of the causative genes h...

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Detalles Bibliográficos
Autores principales: Lu, Qi, Xu, Yang, Zhang, Zeng, Li, Shanshan, Zhang, Zhenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497106/
https://www.ncbi.nlm.nih.gov/pubmed/37705574
http://dx.doi.org/10.3389/fendo.2023.1235040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497106/
https://www.ncbi.nlm.nih.gov/pubmed/37705574
http://dx.doi.org/10.3389/fendo.2023.1235040

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