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Deciphering the binding mechanism of an anti-cancer phytochemical plumbagin with calf thymus DNA using biophysical and in silico techniques

Plumbagin (PLM), a plant derivative, is well known for a wide range of therapeutic effects in humans including anti-cancer, anti-inflammatory, anti-oxidant, and anti-microbial. Cytotoxic and genotoxic potential of this phytochemical has been studied which demands further insight. DNA being a major t...

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Detalles Bibliográficos
Autores principales: Rahaman, Abdul, Anjum, Farah, Kumari, Aknita, Shafie, Alaa, Alee, Mahafooj, Badr, Omnia, Khan, Shaheer Hasan, Ashour, Amal Adnan, Hazazi, Ali, Arif, Sultan, Zeng, Xin-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497110/
https://www.ncbi.nlm.nih.gov/pubmed/37705997
http://dx.doi.org/10.3389/fchem.2023.1248458