Hepatic farnesoid X receptor is necessary to facilitate ductular reaction and expression of heme biosynthetic genes

BACKGROUND: Bile, which contains bile acids, the natural ligands for farnesoid x receptor (FXR), moves from the liver to the intestine through bile ducts. Ductular reaction often occurs during biliary obstruction. A subset of patients with erythropoietic protoporphyria, an inherited genetic mutation...

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Detalles Bibliográficos
Autores principales: Dean, Angela E., Jungwirth, Emilian, Panzitt, Katrin, Wagner, Martin, Anakk, Sayeepriyadarshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497251/
https://www.ncbi.nlm.nih.gov/pubmed/37695073
http://dx.doi.org/10.1097/HC9.0000000000000213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497251/
https://www.ncbi.nlm.nih.gov/pubmed/37695073
http://dx.doi.org/10.1097/HC9.0000000000000213

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