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The kleisin subunit controls the function of C. elegans meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1

The cohesin complex plays essential roles in chromosome segregation, 3D genome organisation, and DNA damage repair through its ability to modify DNA topology. In higher eukaryotes, meiotic chromosome function, and therefore fertility, requires cohesin complexes containing meiosis-specific kleisin su...

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Detalles Bibliográficos
Autores principales: Castellano-Pozo, Maikel, Sioutas, Georgios, Barroso, Consuelo, Prince, Josh P, Lopez-Jimenez, Pablo, Davy, Joseph, Jaso-Tamame, Angel-Luis, Crawley, Oliver, Shao, Nan, Page, Jesus, Martinez-Perez, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497282/
https://www.ncbi.nlm.nih.gov/pubmed/37650378
http://dx.doi.org/10.7554/eLife.84138