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lncRNA read-through regulates the BX-C insulator Fub-1

Though long non-coding RNAs (lncRNAs) represent a substantial fraction of the Pol II transcripts in multicellular animals, only a few have known functions. Here we report that the blocking activity of the Bithorax complex (BX-C) Fub-1 boundary is segmentally regulated by its own lncRNA. The Fub-1 bo...

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Detalles Bibliográficos
Autores principales: Ibragimov, Airat, Bing, Xin Yang, Shidlovskii, Yulii V, Levine, Michael, Georgiev, Pavel, Schedl, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497285/
https://www.ncbi.nlm.nih.gov/pubmed/37643473
http://dx.doi.org/10.7554/eLife.84711