Pneumolysin suppresses the initial macrophage pro‐inflammatory response to Streptococcus pneumoniae

Published data for the Streptococcus pneumoniae virulence factor Pneumolysin (Ply) show contradictory effects on the host inflammatory response to infection. Ply has been shown to activate the inflammasome, but also can bind to MRC‐1 resulting in suppression of dendritic cell inflammatory responses....

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Detalles Bibliográficos
Autores principales: Periselneris, Jimstan, Turner, Carolin T., Ercoli, Giuseppe, Szylar, Gabriella, Weight, Caroline M., Thurston, Teresa, Whelan, Matthew, Tomlinson, Gillian, Noursadeghi, Mahdad, Brown, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497322/
https://www.ncbi.nlm.nih.gov/pubmed/35835695
http://dx.doi.org/10.1111/imm.13546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497322/
https://www.ncbi.nlm.nih.gov/pubmed/35835695
http://dx.doi.org/10.1111/imm.13546

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