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SARS-CoV-2 sublingual vaccine with RBD antigen and poly(I:C) adjuvant: Preclinical study in cynomolgus macaques

Mucosal vaccine for sublingual route was prepared with recombinant SARS-CoV-2 spike protein receptor binding domain (RBD) antigen and poly(I:C) adjuvant components. The efficacy of this sublingual vaccine was examined using Cynomolgus macaques. Nine of the macaque monkeys were divided into three gro...

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Detalles Bibliográficos
Autores principales: Yamamoto, Tetsuro, Tanji, Masanori, Mitsunaga, Fusako, Nakamura, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497375/
https://www.ncbi.nlm.nih.gov/pubmed/37711440
http://dx.doi.org/10.1093/biomethods/bpad017