Medicinal chemistry advances in targeting class I histone deacetylases

Histone deacetylases (HDACs) are a class of zinc (Zn)-dependent metalloenzymes that are responsible for epigenetic modifications. HDACs are largely associated with histone proteins that regulate gene expression at the DNA level. This tight regulation is controlled by acetylation [via histone acetyl...

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Detalles Bibliográficos
Autores principales: Abdallah, Diaaeldin I., de Araujo, Elvin D., Patel, Naman H., Hasan, Lina S., Moriggl, Richard, Krämer, Oliver H., Gunning, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration Publishing 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497394/
https://www.ncbi.nlm.nih.gov/pubmed/37711592
http://dx.doi.org/10.37349/etat.2023.00166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497394/
https://www.ncbi.nlm.nih.gov/pubmed/37711592
http://dx.doi.org/10.37349/etat.2023.00166

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