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Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however, this core complex is non-essential in various species and absent fro...

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Detalles Bibliográficos
Autores principales: Zhu, Zihan, Becam, Isabelle, Tovey, Corinne A., Elfarkouchi, Abir, Yen, Eugenie C., Bernard, Fred, Guichet, Antoine, Conduit, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497398/
https://www.ncbi.nlm.nih.gov/pubmed/37698931
http://dx.doi.org/10.1083/jcb.202212043