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Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes
Microtubule nucleation is mediated by γ-tubulin ring complexes (γ-TuRCs). In most eukaryotes, a GCP4/5/4/6 “core” complex promotes γ-tubulin small complex (γ-TuSC) association to generate cytosolic γ-TuRCs. Unlike γ-TuSCs, however, this core complex is non-essential in various species and absent fro...
Autores principales: | Zhu, Zihan, Becam, Isabelle, Tovey, Corinne A., Elfarkouchi, Abir, Yen, Eugenie C., Bernard, Fred, Guichet, Antoine, Conduit, Paul T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497398/ https://www.ncbi.nlm.nih.gov/pubmed/37698931 http://dx.doi.org/10.1083/jcb.202212043 |
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