Cargando…

PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion

Sister chromatid cohesion, established during replication by the ring-shaped multiprotein complex cohesin, is essential for faithful chromosome segregation. Replisome-associated proteins are required to generate cohesion by two independent pathways. One mediates conversion of cohesins bound to unrep...

Descripción completa

Detalles Bibliográficos
Autores principales: Psakhye, Ivan, Kawasumi, Ryotaro, Abe, Takuya, Hirota, Kouji, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497406/
https://www.ncbi.nlm.nih.gov/pubmed/37592094
http://dx.doi.org/10.1038/s41594-023-01064-x