Precise transcript targeting by CRISPR-Csm complexes

Robust and precise transcript targeting in mammalian cells remains a difficult challenge using existing approaches due to inefficiency, imprecision and subcellular compartmentalization. Here we show that the clustered regularly interspaced short palindromic repeats (CRISPR)-Csm complex, a multiprote...

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Detalles Bibliográficos
Autores principales: Colognori, David, Trinidad, Marena, Doudna, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497410/
https://www.ncbi.nlm.nih.gov/pubmed/36690762
http://dx.doi.org/10.1038/s41587-022-01649-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497410/
https://www.ncbi.nlm.nih.gov/pubmed/36690762
http://dx.doi.org/10.1038/s41587-022-01649-9

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