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Precise transcript targeting by CRISPR-Csm complexes
Robust and precise transcript targeting in mammalian cells remains a difficult challenge using existing approaches due to inefficiency, imprecision and subcellular compartmentalization. Here we show that the clustered regularly interspaced short palindromic repeats (CRISPR)-Csm complex, a multiprote...
Autores principales: | Colognori, David, Trinidad, Marena, Doudna, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497410/ https://www.ncbi.nlm.nih.gov/pubmed/36690762 http://dx.doi.org/10.1038/s41587-022-01649-9 |
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