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Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

The human microbiome influences the efficacy and safety of a wide variety of commonly prescribed drugs. Designing precision medicine approaches that incorporate microbial metabolism would require strain- and molecule-resolved, scalable computational modeling. Here, we extend our previous resource of...

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Detalles Bibliográficos
Autores principales: Heinken, Almut, Hertel, Johannes, Acharya, Geeta, Ravcheev, Dmitry A., Nyga, Malgorzata, Okpala, Onyedika Emmanuel, Hogan, Marcus, Magnúsdóttir, Stefanía, Martinelli, Filippo, Nap, Bram, Preciat, German, Edirisinghe, Janaka N., Henry, Christopher S., Fleming, Ronan M. T., Thiele, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497413/
https://www.ncbi.nlm.nih.gov/pubmed/36658342
http://dx.doi.org/10.1038/s41587-022-01628-0