Structural conservation of antibiotic interaction with ribosomes

The ribosome is a major target for clinically used antibiotics, but multidrug resistant pathogenic bacteria are making our current arsenal of antimicrobials obsolete. Here we present cryo-electron-microscopy structures of 17 distinct compounds from six different antibiotic classes bound to the bacte...

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Detalles Bibliográficos
Autores principales: Paternoga, Helge, Crowe-McAuliffe, Caillan, Bock, Lars V., Koller, Timm O., Morici, Martino, Beckert, Bertrand, Myasnikov, Alexander G., Grubmüller, Helmut, Nováček, Jiří, Wilson, Daniel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497419/
https://www.ncbi.nlm.nih.gov/pubmed/37550453
http://dx.doi.org/10.1038/s41594-023-01047-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497419/
https://www.ncbi.nlm.nih.gov/pubmed/37550453
http://dx.doi.org/10.1038/s41594-023-01047-y

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