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Acute-on-chronic liver failure alters linezolid pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study

BACKGROUND: In acute-on-chronic liver failure (ACLF), adequate antibiotic dosing is challenging due to changes of drug distribution and elimination. We studied the pharmacokinetics of linezolid in critically ill patients with ACLF during continuous renal replacement therapy compared to patients with...

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Detalles Bibliográficos
Autores principales: Tikiso, Tjokosela, Fuhrmann, Valentin, König, Christina, Jarczak, Dominik, Iwersen-Bergmann, Stefanie, Kluge, Stefan, Wicha, Sebastian G., Grensemann, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497461/
https://www.ncbi.nlm.nih.gov/pubmed/37698659
http://dx.doi.org/10.1186/s13613-023-01184-z