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Acute-on-chronic liver failure alters linezolid pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study
BACKGROUND: In acute-on-chronic liver failure (ACLF), adequate antibiotic dosing is challenging due to changes of drug distribution and elimination. We studied the pharmacokinetics of linezolid in critically ill patients with ACLF during continuous renal replacement therapy compared to patients with...
Autores principales: | Tikiso, Tjokosela, Fuhrmann, Valentin, König, Christina, Jarczak, Dominik, Iwersen-Bergmann, Stefanie, Kluge, Stefan, Wicha, Sebastian G., Grensemann, Jörn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497461/ https://www.ncbi.nlm.nih.gov/pubmed/37698659 http://dx.doi.org/10.1186/s13613-023-01184-z |
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