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RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation

The pregenomic RNA (pgRNA) of hepatitis B virus (HBV) serves not only as a bicistronic message RNA to translate core protein (Cp) and DNA polymerase (Pol), but also as the template for reverse transcriptional replication of viral DNA upon packaging into nucleocapsid. Although it is well known that p...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Zheng, Huiling, Lu, Danjuan, Guan, Guiwen, Li, Deyao, Zhang, Jing, Liu, Shuhong, Zhao, Jingmin, Guo, Ju-Tao, Lu, Fengmin, Chen, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497612/
https://www.ncbi.nlm.nih.gov/pubmed/37699883
http://dx.doi.org/10.1038/s41392-023-01573-7