The inhibition of pancreatic cancer progression by K-Ras-overexpressing mesenchymal stem cell-derived secretomes

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor survival. To explore an uncharted function of K-Ras proto-oncogene, K-Ras was activated in mesenchymal stem cells (MSCs) and the effects of MSC conditioned medium (CM) on PDAC were examined. Overexpression of K-Ras elevated PI...

Descripción completa

Detalles Bibliográficos
Autores principales: Huo, Qingji, Li, Kexin, Sun, Xun, Zhuang, Adam, Minami, Kazumasa, Tamari, Keisuke, Ogawa, Kazuhiko, Fishel, Melissa L., Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497626/
https://www.ncbi.nlm.nih.gov/pubmed/37699930
http://dx.doi.org/10.1038/s41598-023-41835-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497626/
https://www.ncbi.nlm.nih.gov/pubmed/37699930
http://dx.doi.org/10.1038/s41598-023-41835-6

Ejemplares similares