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The inhibition of pancreatic cancer progression by K-Ras-overexpressing mesenchymal stem cell-derived secretomes

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor survival. To explore an uncharted function of K-Ras proto-oncogene, K-Ras was activated in mesenchymal stem cells (MSCs) and the effects of MSC conditioned medium (CM) on PDAC were examined. Overexpression of K-Ras elevated PI...

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Detalles Bibliográficos
Autores principales:	Huo, Qingji, Li, Kexin, Sun, Xun, Zhuang, Adam, Minami, Kazumasa, Tamari, Keisuke, Ogawa, Kazuhiko, Fishel, Melissa L., Li, Bai-Yan, Yokota, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497626/ https://www.ncbi.nlm.nih.gov/pubmed/37699930 http://dx.doi.org/10.1038/s41598-023-41835-6

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