Implications of BCRP modulation on PTZ-induced seizures in mice: Role of ko143 and metformin as adjuvants to lamotrigine

Blood–brain barrier (BBB) efflux transporters' overexpression hinders antiepileptic drug brain entry. Breast cancer resistance protein (BCRP) is a major BBB efflux transporter. In the present work, BCRP's role as a mechanism that might contribute to drug-resistant epilepsy (DRE) in a mouse...

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Detalles Bibliográficos
Autores principales: Harby, Sahar A., Khalil, Nehal A., El-Sayed, Norhan S., Thabet, Eman H., Saleh, Samar R., Fathelbab, Mona Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497685/
https://www.ncbi.nlm.nih.gov/pubmed/37067582
http://dx.doi.org/10.1007/s00210-023-02485-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497685/
https://www.ncbi.nlm.nih.gov/pubmed/37067582
http://dx.doi.org/10.1007/s00210-023-02485-7

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