Cargando…

FGF21 alleviates adipose stem cell senescence via CD90 glycosylation-dependent glucose influx in remodeling healthy white adipose tissue

The senescence of adipose stem cells (ASCs) impairs healthy adipose tissue remodeling, causing metabolic maladaptation to energy surplus. The intrinsic molecular pathways and potential therapy targets for ASC senescence are largely unclear. Here, we showed that visceral ASCs were prone to senescence...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Zixin, Zhang, Huiying, Tao, Yan, Zang, Jinhao, Zhao, Jingyuan, Li, Huijie, Wang, Yalin, Wang, Tianci, Zhao, Hui, Wang, Fuwu, Guo, Chun, Zhu, Faliang, Mao, Haiting, Liu, Fengming, Zhang, Lining, Wang, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497791/
https://www.ncbi.nlm.nih.gov/pubmed/37690164
http://dx.doi.org/10.1016/j.redox.2023.102877